Non-enzymatic Glucose Sensor Based on CuO Nanoplates
Main Article Content
Abstract
We have successfully fabricated an electrochemical sensor for non-enzymatic glucose measurement based on copper oxide (CuO) nanoplates. CuO nanoplates were synthesized by a facile hydrothermal method at 180 °C for 23 h without using any surfactants. Field-emission scanning electron microscopy (FE-SEM) and X-ray diffraction (XRD) were used to characterize morphologies and crystal structures of synthesized CuO nanoplates. A mixture of CuO nanoplates and polytetrafluoroethylene with mass ratio 0.15:1 was compressed at 9800 kPa onto platinum (Pt) to form Pt/CuO disk and it has been used as a working electrode for glucose measurement following non-enzymatic approach. Glucose concentration was evaluated by cyclic voltammetry in 0.1 M NaOH solution. This enzyme-free electrochemical method was able to detect glucose with a concentration as low as 0.1 mM. These results show that CuO nanoplates are a promising candidate for non-enzymatic glucose detection.
Keywords
non-enzymatic glucose detection, CuO nanoplates, electrochemical method
Article Details
References
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9. R. Ahmad, N. Tripathy, Y.-B. Hahn, A. Umar, A. A. Ibrahim, and S. H. Kim, A robust enzymeless glucose sensor based on CuO nanoseed modified electrodes, Dalt. Trans., vol. 44, no. 28, (2015), pp. 12488–12492.
10. Z. H. Ibupoto, K. Khun, V. Beni, X. Liu, and M. Willander, Synthesis of novel CuO nanosheets and their non-enzymatic glucose sensing applications, Sensors (Switzerland), vol. 13, no. 6, (2013), pp. 7926–7938.
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12. X. Zhang, G. Wang, W. Zhang, Y. Wei, and B. Fang, Fixure-reduce method for the synthesis of Cu₂O/MWCNTs nanocomposites and its application as enzyme-free glucose sensor, Biosens. Bioelectron., vol. 24, no. 11, (2009), pp. 3395–3398.
13. S. Muralikrishna, K. Sureshkumar, Z. Yan, C. Fernandez, and T. Ramakrishnappa, Non-enzymatic amperometric determination of glucose by CuO nanobelt graphene composite modified glassy carbon electrode, J. Braz. Chem. Soc., vol. 26, no. 8, (2015), pp. 1632–1641.
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