The LC-MS/MS method for analysis of carbamate group applied to determine the residues of pesticides in Vietnam agricultural products
Main Article Content
Abstract
For the purpose of determining the residues of some recently registered pesticides to Vietnam agricultural products, a quick and precise approach based on a modification of QuEChERS extraction and liquid chromatography tandem mass spectrometry (LC-MS/MS) has been studied. By using the LC-MS/MS method, carbamate pesticide residues were identified and measured on a variety of sample matrices. The approach performed well in the concentration ranges between 0.1 and 200 ppb. All the insecticides used in the testing had LOQ values that less than 10 ppb and the repeatability less than 20% RSD. For a variety of agricultural goods, including cabbage, truffle, rice, grape, the approach has been successfully used.
Keywords
LC-MS/MS, carbamate group, residues pesticides, QuEchERS
Article Details
References
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feedstuff of farm animals drawn from Greece,
Chemosphere, 2010, 80(5), p. 504-512,
https://doi.org/10.1016/j.chemosphere.2010.04.069
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method employing acetonitrile extraction/ partitioning
and “dispersive solid-phase extraction” for the
determination of pesticide residues in produce. J
AOAC Int, 2003. 86(2), p. 412-431. PMID: 12723926
[7] Lesueur, C., et al., Analysis of 140 pesticides from
conventional farming foodstuff samples after
extraction with the modified QuECheRS method. Food
control, 2008, 19(9),p.906-914,
https://doi.org/10.1016/j.foodcont.2007.09.002
[8] Mi Young Yin et al., A multiresidue method for the
determination of 118 pesticides in vegatable juice by
Gas-Chromatography- Mass spectrometry and liquid
Chromatography-Tandem Mass spectrometry,
J.Agric.Food Chem, 57. 10095-10101, 2009,
https://doi.org/10.1021/jf902712v
[9] Howard D.Dewald. Electrospray Ionization Mass
Spectrometry: Fundamentals, Instrumentation, and
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Publications, USA, 1999
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practice, Journal of Mass spectrometry, 1997, 32(7),
pp. 677-688,
https://doi.org/10.1002/(SICI)1096-
9888(199707)32:7<677::AID-JMS536>3.0.CO;2-G
[11] Niesen W.M.A, Tinke A.P., Liquid chromatographymass spectrometry general principles and
instrumentation, Journal of chromatography A, 1995,
703(1-2), p. 37-57,
https://doi.org/10.1016/0021-9673(94)01198-N
[12] Sagratini, G., et al., Analysis of carbamate and
phenylurea pesticide residues in fruit juices by solidphase microextraction and liquid chromatography–
mass spectrometry, Journal of chromatography A.
2007, 1147(2), p. 135-143,
https://doi.org/10.1016/j.chroma.2007.02.066
[13] CSN EN 15662, Foods of Plant origin – Multimethod
for the determination of pesticide residues using GC
and LC-based analysis following acetonitrile
extraction/partitioning and clean-up by dispersive
SPE- modular QuEChERS- method, 2018.
Classification of Pesticides by Hazard and Guidelines
to Classification, 2019 Editon, 2020.
[2] Gupta, R.C., Classification and uses of
organophosphates and carbamates, in Toxicology of
Organophosphate & Carbamate Compounds, Elsevier,
2006 p. 5-24.
[3] Popovska-Gorevski, M., M.L. Dubocovich, and
R.V.J.C.r.i.t. Rajnarayanan, Carbamate insecticides
target human melatonin receptors, Chem Res Toxicol,
2017, 30(2), p. 574-582,
https://doi.org/10.1021/acs.chemrestox.6b00301
[4] Moffett, D.B. Public health impacts of
organophosphates and carbamates, in Toxicology of
Organophosphate & Carbamate Compounds. Elsevier,
2006, p. 599-606.
[5] Tsiplakou, E., et al., Pesticides residues in milks and
feedstuff of farm animals drawn from Greece,
Chemosphere, 2010, 80(5), p. 504-512,
https://doi.org/10.1016/j.chemosphere.2010.04.069
[6] Anastassiades, M., et al., Fast and easy multiresidue
method employing acetonitrile extraction/ partitioning
and “dispersive solid-phase extraction” for the
determination of pesticide residues in produce. J
AOAC Int, 2003. 86(2), p. 412-431. PMID: 12723926
[7] Lesueur, C., et al., Analysis of 140 pesticides from
conventional farming foodstuff samples after
extraction with the modified QuECheRS method. Food
control, 2008, 19(9),p.906-914,
https://doi.org/10.1016/j.foodcont.2007.09.002
[8] Mi Young Yin et al., A multiresidue method for the
determination of 118 pesticides in vegatable juice by
Gas-Chromatography- Mass spectrometry and liquid
Chromatography-Tandem Mass spectrometry,
J.Agric.Food Chem, 57. 10095-10101, 2009,
https://doi.org/10.1021/jf902712v
[9] Howard D.Dewald. Electrospray Ionization Mass
Spectrometry: Fundamentals, Instrumentation, and
Applications, Richard B. Cole (Ed.), ACS
Publications, USA, 1999
[10] Simon J.Gaskell. Electrospr1ay: principles and
practice, Journal of Mass spectrometry, 1997, 32(7),
pp. 677-688,
https://doi.org/10.1002/(SICI)1096-
9888(199707)32:7<677::AID-JMS536>3.0.CO;2-G
[11] Niesen W.M.A, Tinke A.P., Liquid chromatographymass spectrometry general principles and
instrumentation, Journal of chromatography A, 1995,
703(1-2), p. 37-57,
https://doi.org/10.1016/0021-9673(94)01198-N
[12] Sagratini, G., et al., Analysis of carbamate and
phenylurea pesticide residues in fruit juices by solidphase microextraction and liquid chromatography–
mass spectrometry, Journal of chromatography A.
2007, 1147(2), p. 135-143,
https://doi.org/10.1016/j.chroma.2007.02.066
[13] CSN EN 15662, Foods of Plant origin – Multimethod
for the determination of pesticide residues using GC
and LC-based analysis following acetonitrile
extraction/partitioning and clean-up by dispersive
SPE- modular QuEChERS- method, 2018.